Here, professionals and patients will find short summaries (“abstracts”) of scientific publications concerning the agents used in our products. If available, a link to the online-version of the publication will be given.
Wilson JP et al. 2015; Decorporation of systemically distributed americium by a novel orally administered diethylenetriaminepentaacetic Acid (DTPA) formulation in beagle dogs; Health Phys. 108(3):308-18
Study design: Beagle dogs received various doses of NanoDTPATM capsules to decorporate administered 241Americium (241Am). Efficacy of NanoDTPATM was compared to intravenously … » More
Shankar GN et al. 2014; Evaluating the toxicity of novel Zn-DTPA tablet formulation in dogs and rats; Drug Dev. Res. 75(1):37-46
Study design: Beagle dogs were treated with increasing doses of trisodium zinc pentetate (Zn-DTPA) in a novel oral solid tablet form for seven days to determine its toxicity … » More
Schwartz JB et al. 2016; Response of vitamin D concentration to vitamin D3 administration in older adults without sun exposure: A randomized double-blind trial; J. Am. Geriatr. Soc. 64(1):65-72
Study design: Randomized double-blind investigation to evaluate the 25 OHD levels in elderly nursing home residents after 16 weeks when 800, 2 000 or 4 000 IU/day or 50 000 … » More
Välimäki VV et al. 2016; How well are the optimal serum 25OHD concentrations reached in high-dose intermittent vitamin D therapy? A placebo-controlled study on comparison between 100 000 IU and 200 000 IU of oral D3 every 3 months in elderly women; Clin. Endocrinol. 84(6):837-44
Study design: Elderly women received 100 000 or 200 000 IU of vitamin D3 or placebo orally every 3 months plus 1 g of calcium daily over one year to test intermittent … » More
Almeida MR et al. 2015; Effects of maternal vitamin B6 deficiency and over-supplementation on DNA damage and oxidative stress in rat dams and their offspring; Food Chem. Toxicol. 80:201-5
Study design: Female rats were fed with standard diet, 30 mg/kg vitamin B6 supplemented diet or deficient diet during mating, pregnancy and lactation. The offspring was … » More
Shobeiri F et al. 2015; Clinical effectiveness of vitamin E and vitamin B6 for improving pain severity in cyclic mastalgia; Iran. J. Nurs. Midwifery Res. 20(6):723-7
Study design: Female patients suffering from cyclic mastalgia received 200 IU vitamin E or 40 mg vitamin B6 daily for 2 months, randomised in a double-blinded clinical trial, … » More
Seishima R et al. 2016; Sulfasalazine, a therapeutic agent for ulcerative colitis, inhibits the growth of CD44v9+ cancer stem cells in ulcerative colitis-related cancer; Clin. Res. Hepatol. Gastroenterol. 40(4):487-93
Study design: This retrospective study compared the expression of cancer stem cell surface marker CD44v9+ and proliferation of CD44+ cancer cells in patients treated with … » More
Baset MA et al. 2015; Effectiveness of methotrexate and sulfasalazine alone versus methotrexate and sulphasalazine combination in the treatment of rheumatoid arthritis; Bangladesh J. Med. 26(2):67-75
Study design: In this comparative descriptive study 30 patients suffering from rheumatoid arthritis (RA) received either methotrexate (MTX), sulfasalazine (SSZ) or MTX plus … » More
Montejo C et al. 2004; Time delay avoids interaction between guar gum and sulphadiazine after oral administration; J. Drug Deliv. Sci. Technol. 14(5):395-9
Study design: In a two-way-cross-over design volunteers received sulphadiazine alone or one hour after an oral dose of guar gum. Drug and metabolite levels were measured up … » More
Köksal ZS et al. 2016; In vivo efficacy of drugs acting on Toxoplasma gondii combined with immunomodulators; Jpn. J. Infect. Dis. 69(2):113-7
Study design: Treatment of T. gondii infected mice with various combinations of sulphadiazine and pyrimethmamine plus levamisole or echinacea to determine their influence on … » More